This study is an expanded version of the 2013 Man vs. Machine study, which compared NeuroQuant® measures of brain volume with the radiologist’s traditional approach in outpatients with mild or moderate traumatic brain injury (TBI).  In the current study, NeuroQuant® found significantly higher rates of atrophy (50.0%), abnormal asymmetry (83.3%), and progressive atrophy (70.0%) than the radiologists (12.5%, 0%, and 0%, respectively).  Overall, NeuroQuant® was more sensitive for detecting at least one sign of atrophy, abnormal asymmetry, or progressive atrophy (95.8%) than the traditional radiologist’s approach (12.5%). 

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Ross, DE, AL Ochs, ME DeSmit, JM Seabaugh, MD Havranek (2015).  Man vs. Machine Part 2:  Comparison of radiologists’ interpretations and NeuroQuant® measures of brain asymmetry and progressive atrophy in patients with traumatic brain injury. Journal of Neuropsychiatry and Clinical Neurosciences 27:147-152.  To view the PubMed citation of this paper, click here.