This study compared NeuroQuant® with the radiologist’s traditional approach, based on visual inspection, in 20 outpatients with mild or moderate traumatic brain injury (TBI).  Each MRI was analyzed with NeuroQuant®, and the resulting volumetric analyses were compared with the attending radiologist’s interpretation.  The radiologist’s traditional approach found atrophy in 10.0% of patients.  NeuroQuant® found atrophy in 50.0% of patients.  NeuroQuant® was more sensitive for detecting brain atrophy than the traditional radiologist’s approach. 

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Ross, DE, AL Ochs, JM Seabaugh, CR Shrader (2013). Man vs. machine:  Comparison of radiologists’ interpretations and NeuroQuant® volumetric analyses of brain MRIs in patients with traumatic brain injury. Journal of Neuropsychiatry and Clinical Neurosciences 25:1-8.  To view the PubMed citation of this paper, click here.